or up to three months after a stay in an area where malaria is endemic ( map ) – whether accompanied by other signs and symptoms or not – must be considered as a malaria attack until proved otherwise and requires swift
Always keep a thermometer on hand and check your body temperature regularly (every eight hours) if you
feel unwell, even if you do not think that you have a fever! The first days of a malaria infection can often be
relatively mild and can easily be confused with other conditions, but the longer you wait to start the correct
treatment, the higher the risk of severe illness, complications and even death. The only way to confirm (or
rule out) a malaria diagnosis is by means of a blood test (“thick drop” and “smear” in combination with a
rapid test). After you return, you should insist on this test being done urgently whenever you
have a fever (until three months after leaving the malaria zone) and on obtaining the result within a few
The use of any of the options summarised below for emergency treatment for malaria, implemented at your
own initiative, can result in dangerous errors and is absolutely not recommended!
In the case of warning symptoms such as fever lasting longer than three days, dark urine, jaundice,
shortness of breath or reduced consciousness, an urgent hospitalisation is indicated.
The following treatment schedules have been selected, because their effectiveness is close to 100 %. Many
other schedules are possible, but they are definitely less effective.
A. ATOVAQUONE 250mg/PROGUANIL 100mg®
B. RIAMET (artemeter 20mg + lumefantrine 120mg)®
C. QUININE + DOXYCYCLINE
ATOVAQUONE 250mg/PROGUANIL 100mg ® : four tablets/day for three days, to be taken with food.
RIAMET® (artemeter 20mg + lumefantrine 120mg) : 6 x 4 tablets: four tablets at the time of diagnosis, four tablets eight hours later and then four tablets every 12 hours for another two days, to be taken with food. Often a follow-up with ECG is indicated.
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Source: Institute for Tropical Medicine – Antwerp – Belgium